Polyethylene Glycol - PEG - a PG alternative

[sirevelyntremble]

For those with allergies to PG, there is PEG

PG Sensitivity

Another base type: PEG
PEG is a viable alternative base especially as it presents flavours better than either PG or VG. It has been extensively used in prefilled cartos for this reason, especially when supplied from the Boge-Dekang factories. However it is the most usual base type to experience contamination issues with DEG, a toxic glycol made in the same manufacturing facilities from similar feedstocks and therefore liable to cross-contamination issues. If PEG can be located in a high-quality form and efficiently tested as absolutely free from DEG, it is a good alternative base material [8].

From Wiki P

Polyethylene glycol (PEG) is a polyether compound with many applications from industrial manufacturing to medicine. The structure of PEG is (note the repeated element in parentheses):

H-(O-CH2-CH2)n-OH
PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight

Medical uses[edit]
PEG is the basis of a number of laxatives (e.g., macrogol-containing products, such as Movicol and polyethylene glycol 3350, or SoftLax, MiraLAX,ClearLAX, Osmolax or GlycoLax). Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. The preparation is sold under the brand names GoLYTELY, GaviLyte C, NuLytely, GlycoLax, Fortrans, TriLyte, Colyte, Halflytely, Softlax, Lax-a-Day, ClearLax and MoviPrep. In the United States, MiraLAX and Dulcolax Balance are sold without prescription for short-term relief of chronic constipation.

Miralax is currently FDA approved for adults for a period of seven days, and is not approved for children.[6] A 2007 comparison showed that patients suffering from constipation had a better response to PEG medications than to tegaserod.[7] These medications soften the fecal mass by osmotically drawing water into the GI tract. It is generally well tolerated; however, side effects are possible bloating, nausea, gas, and diarrhea (with excessive use).

When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. This makes for a longer-acting medicinal effect and reduces toxicity, and allows longer dosing intervals. Examples include PEG-interferon alpha, which is used to treat hepatitis C, and PEGfilgrastim (Neulasta), which is used to treat neutropenia. It has been shown that polyethylene glycol can improve healing of spinal injuries in dogs.[8] One of the earlier findings, that polyethylene glycol can aid in nerve repair, came from the University of Texas (Krause and Bittner).[9] Polyethylene glycol is also commonly used to fuse B-cells with myeloma cells in monoclonal antibody production.

PEG is used as an excipient in many pharmaceutical products. Lower-molecular-weight variants are used as solvents in oral liquids and soft capsules, whereas solid variants are used as ointment bases, tablet binders, film coatings, and lubricants.[10]

PEG is also used in lubricating eye drops.

If it's good enough to put in your eyes (or your a**) then it's as safe if not safer than PG. I think it seems a better alternative to PG if it can be sourced from non-Chinese sources. Needs to be researched. In the future this could become the replacement for PG for those with PG allergies, or just in general if it is better for you than PG.

I don't know how it compares with PG for recommended max intake daily (4 ml for PG - more than that can make you feel a bit sick) .... but vendors take note, this substance could be the "gluten-free" of the vaping world

 

[oldhippydude]

Give it a go and let me know how you are getting on in ten years.

 

[sirevelyntremble]

Give it a go and let me know how you are getting on in ten years.

 

[steffijade]

Give it a go and let me know how you are getting on in ten years.

I seem to recall Dave Dorn vaped PEG juice.

I know it's not 10 years, but I reckon he's been vaping a good 5 years if not longer. Could always ask him?

 

[v4ping_th3_b4rrel]

We used to use peg as a cutting agent....mix peg and silica carbide together and you get a slurry that is used in wire saws to cut silicone for the solar industry....wouldn't wamtvto vape slurry thats for sure. Would be great if peg was safe as I can get it for free....

 

[puppiesrdelicious]

The FDA GRAS rating for PG is not for inhalation.

Additionally one should only inhale pharmaceutical grade Gs.

PSA: 'USP' is NOT a grade.