interesting paper on nicotine

[Mr Ripple]

No, not slow release @StrawberryRipple . What @Ment said is right, this substance prevents or slows the nic being metabolised so it floats around in your system longer. It’s not slow release, more like slow breakdown.

Interested by article, thanks @dahut . I wonder what the implications are for salt nic? As I understand it it doesn’t oxidise the way freebase does.

That would explain what folks say regarding salt slowing steeping!

 

[dahut]

The link below is an interesting read if you can follow the jargon.
I understand it that nicotyrine acts by making nicotine become slow release?

Mind you everything on the subject so far appears to at the "hypothesis" stage which means its still theory and not proved as yet.

https://www.sciencedirect.com/science/article/pii/S0306987715002212

that's the link i dropped in the opening post mate

 

[zouzounaki]

If that theory is right about salt inhibiting steeping it would imply that salt would be less satisfying in the longer term as the metabolism would break it down more quickly than a well steeped standard nic liquid. If it’s right enough that steeping involves nic reacting with compounds in the flavour concentrated and becoming partially oxidised, that is.

 

[Mr Ripple]

that's the link i dropped in the opening post mate

Doh!

 

[Kezza1.0]

I don't think I want to irreversibly inhibit my CYP2A6.

 

[zouzounaki]

I don't think I want to irreversibly inhibit my CYP2A6.

Why not? It attenuates nicotine withdrawal.

 

[Kezza1.0]

Who knows what else it does? It might negatively affect your libido, or ability to do the backstroke.

 

[Fuctifino]

 

[zouzounaki]

Could it be that they are Michael acceptors...?

https://en.m.wikipedia.org/wiki/Michael_reaction

 

[zouzounaki]

Who knows what else it does? It might negatively affect your libido, or ability to do the backstroke.

Did you see what it did to @Badboybez ?