Hi Midnight, sorry for the late reply my wife reminded me I had a life "outside of bloody vaping" and I had to do some chores, Yeah I found PG gave me a really sore throat and swollen glands, I think i'm allergic to it in large amounts so I tried a few different mixes including 100% VG which was nice but I was filling up my tank three times a day, so I settled on 50-50 and since then, well lets just say I dont have trouble with constipation !!!!