There are different degrees of reaction to PG. An allergy to it can cause soreness and blotches etc from even a small amount. An intolerance usually reguire more pg to cause the problem. My son can get away with 10_20% PG before he starts to get the reaction. Worth trying the 50/50 mix to see if it improves your problem.
Going too high with VG would require it to be thinned slightly with distilled water so the wicking ports can keep up with the e- liquid.
Could possibly be the juice your using, especially if there's a lot of additives in it. I get dry and sore itchy skin if I vape pre mixed juice that contains a lot of sweeteners in it.