french and nicotene with covid-19

[Crewella]

I'm interested ................ but my first reaction was, I'm afraid, a big cheesy grin at the unexpected angle!

 

[vapesmarter]

Farsalinos was the first to identify the lack of smokers in China. His study is in pre-print so it’s not been covered yet - but I have a copy on my desktop.

Two separate studies have gone on to identify something similar occurring in Europe.

Thoughts are that nicotine bonds to the receptors used by the virus. Thus blocking it.

There is a growing body of experts who believe this one has legs.

View attachment 216282

you saw it here first boys and girls

“vapesmarter saviour of the planet”

Thankyou thankyou ‘‘twas” nothing.....

 

[Mitz]

Farsalinos was the first to identify the lack of smokers in China. His study is in pre-print so it’s not been covered yet - but I have a copy on my desktop.

Two separate studies have gone on to identify something similar occurring in Europe.

Thoughts are that nicotine bonds to the receptors used by the virus. Thus blocking it.

There is a growing body of experts who believe this one has legs.

View attachment 216282

ACE2 has already been identified as playing an important role with SARS and this virus.

https://www.sciencedaily.com/releases/2020/04/200422132556.htm

 

[oldhippydude]

Here is an abstract of a paper that points in a different direction https://www.researchgate.net/public..._Expression_of_ACE2_the_Receptor_of_2019-nCov

In current severe global emergency situation of 2019-nCov outbreak, it is imperative to identify vulnerable and susceptible groups for effective protection and care. Recently, studies found that 2019-nCov and SARS-nCov share the same receptor, ACE2. In this study, we analyzed four large-scale datasets of normal lung tissue to investigate the disparities related to race, age, gender and smoking status in ACE2 gene expression. No significant disparities in ACE2 gene expression were found between racial groups (Asian vs Caucasian), age groups (>60 vs <60) or gender groups (male vs female). However, we observed significantly higher ACE2 gene expression in smoker samples compared to non-smoker samples. This indicates the smokers may be more susceptible to 2019-nCov and thus smoking history should be considered in identifying susceptible population and standardizing treatment regimen.

 

[Mawsley]

Here is an abstract of a paper that points in a different direction https://www.researchgate.net/public..._Expression_of_ACE2_the_Receptor_of_2019-nCov

In current severe global emergency situation of 2019-nCov outbreak, it is imperative to identify vulnerable and susceptible groups for effective protection and care. Recently, studies found that 2019-nCov and SARS-nCov share the same receptor, ACE2. In this study, we analyzed four large-scale datasets of normal lung tissue to investigate the disparities related to race, age, gender and smoking status in ACE2 gene expression. No significant disparities in ACE2 gene expression were found between racial groups (Asian vs Caucasian), age groups (>60 vs <60) or gender groups (male vs female). However, we observed significantly higher ACE2 gene expression in smoker samples compared to non-smoker samples. This indicates the smokers may be more susceptible to 2019-nCov and thus smoking history should be considered in identifying susceptible population and standardizing treatment regimen.

It's a pre-print, and one that has attracted a fair bit of criticism. It's why I've not covered Farsalinos' yet either.

 

[Mawsley]

The thing that makes me want to believe nic can help in this case is the volume of rabid anti-vape campaigners who are doing an absolute nut over the possibility.

And the thing that concerns me is the volume of pre-prints being treated like published studies. They haven't been peer-reviewed yet they're being punted out to the media as though they are the same. It's piss-poor science, and to Farsalinos' credit that he hasn't done this with his paper - unlike the ones attacking nicotine. It's that shoddy approach that makes me feel their work is a bit bogus.

It'll all come out in the wash though, hopefully.

 

[oldhippydude]

Wanting to believe, makes me cautious.

 

[oldhippydude]

https://www.dw.com/en/does-nicotine-help-against-the-new-coronavirus/a-53260336

 

[Leni]

Wouldn’t using nicotine patches be redundant anyway ... in that the nicotine goes straight into the blood stream bypassing the lungs? Maybe I’ve misunderstood, but I’d have thought the nicotine would need to enter the body through the lungs

 

[vapesmarter]

Wouldn’t using nicotine patches be redundant anyway ... in that the nicotine goes straight into the blood stream bypassing the lungs? Maybe I’ve misunderstood, but I’d have thought the nicotine would need to enter the body through the lungs

there is a lot of debate on the bloodstream and nic some people are saying a link between the blood and oxygen being absorbed from the alveoli it's all science and a quick fix but....if it did work.......