If your unsure about this, you really need to ask the questions, without being melodramatic, getting it wrong could result in death or dismemberment.
You need to understand how your coil resistance relates to the current draw on your cell so you can assess weather firing that coil with that cell is safe.
This is absolutely no shit seriously important. Sub ohming is just as safe as any other kind of vaping, IF THE VAPER FULLY UNDERSTANDS WHAT THEY ARE DOING. If they dont, its as potentially lethal as a loaded gun.
You need to know and be able to work out
Coil resistance and how it relates to current draw on your device.
Amp limit on your cells and if your buipd is within those limits.
Difference in icr and imr/inr (inr is samsung cells, accept they are imr) and hybrid cells and how each applies to your usage.
Indications of an unhappy cell/build (hot button/tube indicating shorts) and what to do vis a vis when to either rip the mod apart or throw it in one direction whilst running in the other.
This all sounds scary because its meant to, lithium cells going bad is really not something to fuck about with, I happily vape sub ohm on every device I have in circulation, my most used rig is a .3ohm dripper, but I know that is within the limits of most of my cells, I have lower limit cells that are only good for 10a or .6ohm builds, they are extremely good cells but they have their limits so I stay within them. You need to know both your cell limits and what your builds will draw so you can tell if your vaping safe or not.
You only need be concerned with constant current, forget the pulse bullshit, thats a stupid assumption to make, if your above constant current dont fire it.