E-cigarettes become the most popular UK 'quitting aid' with 1.3 million users

[anthonyb]

You forgot to mention all the other bits and bobs ie: the horse serum, hydrocortisone, antibiotics, cholera toxin and insulin. The way I read it, is they hit the cells with a cocktail which included a potentially fatal nicotine hit. Please shoot me down if i'm wrong.

 

[Tubbyengineer]

The paper is here - http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067252#abstract0

From my reading of this it seems that the dosage level of nicotine used was the LD50 dose which is way higher (several orders of magnitude higher) than it would ever reach for any eCig or even cigarette.

I could be wrong about this - I'm very out of practice at reading scientific papers, but if we have any biologists here they might like to take a closer look at the paper.

Having had a quick read of the paper they say that smoking 1 cigarette gives approx 1mG of nicotine results in a nicotine concentration (in blood plasma) of 15ng/ml (thats 15 nanograms per millilitre), However the concentration the used in the test was 811 ng/ml thats 54, Yes 54 times higher. Who in there right mind could possibly smoke 54 cigs at once?