I have found that some juices (usually slightly bitter ones like Black Magic (chocolate, coffee and a little tabacco)) has given me a headache if i vape too much even when i drink lots of water.
Hot vapes (when i built my first coil without using a VV mod (drawing straight from a 18650 battery)) have irritated my throat if i use them too much so i just switch back to one of my other mods.
Increased waist line, since i have my full sense of taste back my sweet tooth returned (luckily can be held at bay by some vapes).
Decreased bank balance due to shinyitis, it seems to be contagious.