I'm having the vaccine when it comes out poll

[Mitz]

Not anti-vax, and not unexpected as there are similar reactions to other vaccines. Just a point.

https://www.theguardian.com/world/2...extreme-allergy-sufferers-regulators-reaction

Interesting that just about as many people in the trials who had the placebo experienced an allergic reaction just like those who actually had the vaccine. So the vaccine is no more likely to cause an allergic reaction than an administered placebo.

 

[zouzounaki]

Interesting that just about as many people in the trials who had the placebo experienced an allergic reaction just like those who actually had the vaccine. So the vaccine is no more likely to cause an allergic reaction than an administered placebo.

aye, i noticed that. i don’t think it said what the placebo group were injected with. i think the oxford vaccine placebo group were given an existing and known to be safe vaccine. so they are injected with something, that could potentially cause a reaction in some folks.

i had radio 4 on earlier and some expert on there was saying that rna might be the likely cause of the reaction in susceptible people, triggering an unexpected immune response.

 

[oldhippydude]

Interesting that just about as many people in the trials who had the placebo experienced an allergic reaction just like those who actually had the vaccine. So the vaccine is no more likely to cause an allergic reaction than an administered placebo.

Nocebo
From Wikipedia, the free encyclopedia
Jump to navigation Jump to search A nocebo effect is said to occur when negative expectations of the patient regarding a treatment cause the treatment to have a more negative effect than it otherwise would have.[1][2] For example, when a patient anticipates a side effect of a medication, they can suffer that effect even if the "medication" is actually an inert substance.[1] The complementary concept, the placebo effect, is said to occur when positive expectations improve an outcome. Both placebo and nocebo effects are presumably psychogenic, but they can induce measurable changes in the body.[1] One article that reviewed 31 studies on nocebo effects reported a wide range of symptoms that could manifest as nocebo effects including nausea, stomach pains, itching, bloating, depression, sleep problems, loss of appetite, sexual dysfunction and severe hypotension.[

 

[Mitz]

aye, i noticed that. i don’t think it said what the placebo group were injected with. i think the oxford vaccine placebo group were given an existing and known to be safe vaccine. so they are injected with something, that could potentially cause a reaction in some folks.

i had radio 4 on earlier and some expert on there was saying that rna might be the likely cause of the reaction in susceptible people, triggering an unexpected immune response.

I thought placebo injections usually consisted of saline. May well have been another vaccine tho just to compare the immune responses.

It seems both people who had a reaction have a long history of allergic reactions and both need to carry an epi-pen. People have reactions to the flu jab too.

 

[vapesmarter]

I thought placebo injections usually consisted of saline. May well have been another vaccine tho just to compare the immune responses.

It seems both people who had a reaction have a long history of allergic reactions and both need to carry an epi-pen. People have reactions to the flu jab too.

people can get a reaction from saline like you would if you stuck any needle into the body like brushing itching of the site etc but some of the trials they do now the patient is injected with a standard flu jab or alike mainly because if you get no reaction at the site the patient then jumps onto google when they get home and reads "no reaction to a trial vaccine then you have had a saline injection"

 

[zouzounaki]

I thought placebo injections usually consisted of saline. May well have been another vaccine tho just to compare the immune responses.

It seems both people who had a reaction have a long history of allergic reactions and both need to carry an epi-pen. People have reactions to the flu jab too.

i just searched google and it looks like in the pfizer study the placebo was actually saline. the oxford one definitely used an existing vaccine, they’ve mentioned it a few times on telly news interviews.

 

[Mitz]

Nocebo
From Wikipedia, the free encyclopedia
Jump to navigation Jump to search A nocebo effect is said to occur when negative expectations of the patient regarding a treatment cause the treatment to have a more negative effect than it otherwise would have.[1][2] For example, when a patient anticipates a side effect of a medication, they can suffer that effect even if the "medication" is actually an inert substance.[1] The complementary concept, the placebo effect, is said to occur when positive expectations improve an outcome. Both placebo and nocebo effects are presumably psychogenic, but they can induce measurable changes in the body.[1] One article that reviewed 31 studies on nocebo effects reported a wide range of symptoms that could manifest as nocebo effects including nausea, stomach pains, itching, bloating, depression, sleep problems, loss of appetite, sexual dysfunction and severe hypotension.[

It's a tricky one for the doctors I'm sure. If negative expectations can cause psychosomatic symptoms in the placebo group then the same expectations can cause the same psychosomatic symptoms in the vaccine group.

 

[Mitz]

i just searched google and it looks like in the pfizer study the placebo was actually saline. the oxford one definitely used an existing vaccine, they’ve mentioned it a few times on telly news interviews.

Saline too I think. Unless they used different things in different locations. Funny thing is I also actually think I recall previously hearing another vaccine was used.

"Participants are being randomised to receive two doses of either the potential vaccine or a saline control, four weeks apart, with twice as many participants receiving the potential vaccine than the saline control. The trial is assessing efficacy and safety of the potential vaccine in all participants, and local and systemic reactions and immune responses will be assessed in 3,000 participants."


https://www.astrazeneca.com/media-c...e-iii-clinical-trial-initiated-in-the-us.html

 

[Leni]

REG 174 INFORMATION FOR UK RECIPIENTS

https://assets.publishing.service.g...B1pOR0ajrD4r83LrjAgguhm3iu008YMgS_QUZCBAix9Jc

Interesting info. In the ‘very common’ and ‘common’ side effects sections they have things like headaches, joint pain and nausea listed, in the ‘uncommon’ side effects section they have a rather vague ‘feeling unwell’ listed

 

[Jd_]

Interesting info. In the ‘very common’ and ‘common’ side effects sections they have things like headaches, joint pain and nausea listed, in the ‘uncommon’ side effects section they have a rather vague ‘feeling unwell’ listed

From whats been reported here, basically what u should expect is to feel varying degrees of like crap with a slight fever overnight and like someone punched u in the arm.

Added: they claim this is a desirable reaction because what you r experiencing is your immune system being kick started, so who knows