Horizon: Dr Michael Mosley
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knome
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Keep 'em coming but I understand why you call it the twattersphere. Will Dr Mosley go from nice chap to gurning idiot in three hours?
EV_Phil
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Mark
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Mark
Legend
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Mark
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Looks like we have a pretty good idea of the programme's synopsis and conclusions....what do you think?
http://vapers.org.uk/smoke-and-mirrors-the-truth-about-vaping/
Horizon: E-Cigarettes: Miracle or Menace?
BBC Two – 9.30pm on Sunday 22nd May 2016
When the editor of the BBC science series Horizon asked me if I fancied making a programme about e-cigarettes that would involve “vaping” (inhaling nicotine-laden vapour) for a month my initial reaction was: “Hell, no.”
Then I thought about it a bit. I was worried that if I took it up I might get addicted (I’d never smoked), but I was also curious. What would it be like? What effect would it have on me? There has been a huge surge in the use of e-cigarettes over the past couple of years, yet very few studies on the effects of vaping on non-smokers. Time, I decided, to do one, with me as the subject.
I hate cigarettes, really hate them. I’ve never smoked, partly because when I was young I didn’t see the point, but mainly because when I was about 12 my dad offered me £100 if I didn’t smoke before the age of 18. I can’t remember if he ever paid me.
If I was even a little tempted to smoke, going to medical school put me off. One of the first patients I saw was Sarah, a 65-year-old woman who was dying of emphysema, a very common disease of the lungs caused by smoking. Even with an oxygen mask she struggled for breath. She’d been smoking 40 a day since she was 15 and she reckoned that she’d spent about £90,000 on cigarettes (at today’s prices it would be more like £290,000).
I also remember a young man called Alex with Buerger’s disease, a relatively rare condition where you get inflammation and clotting in your arteries and veins. Almost everyone who has Buerger’s smokes, and quitting smoking is the only way to stop it progressing. Despite knowing the risks Alex just couldn’t stop. He eventually developed gangrene and had to have a limb amputated.
Fans of e-cigarettes claim that vaping could help people like Alex and Sarah, either by making it easier for them to quit or by providing a safer way for them to get a nicotine hit. It is said that smokers smoke for the nicotine but die from the tar, so why not give them one and not the other?
Critics, however, say that we are gambling with a technology we don’t understand and that there is no convincing evidence that e-cigarettes help people to quit smoking. It may even encourage non-smokers to start.
There is a huge amount at stake. A billion people worldwide spend about £500 billion a year on cigarettes and about half will die of smoking-related diseases. In the UK alone smoking kills about 100,000 a year. If e-cigarettes take even a small fraction of the cigarette market, that is a lot of money and a lot of lives.
Some countries have warily embraced e-cigarettes, while others have effectively banned them. The UK has so far adopted a liberal approach, but in a few days’ time there will come into force European legislation that will limit the size of refills and the nicotine content of the fluids. Vaping will become more restricted.
So who’s right? Are e-cigarettes one of the greatest public health measures invented, with the potential to save millions of lives, or are they just another cunning way to keep us hooked on nicotine? I was keen to find out.
I started by having a range of physical and mental tests, including cognitive tests such as reaction times, then headed for my nearest e-cigarette shop. They come in lots of different shapes and sizes but all work on the same principle: there’s a battery that powers a heating element, a coil. There’s a chamber into which you pour your “e-liquid” which usually, but not always, contains nicotine. The heat from the coil turns the liquid into vapour, which you then inhale. There’s no burning and therefore fewer noxious chemicals involved. The e-liquids come in many flavours, from pina colada to menthol. I went for mint.
I bought a nice, geeky-looking device, with a big, shiny canister and lots of buttons. Then I went home to start vaping. I’d been given a schedule that began gently, then rapidly built to the point where I was taking about 120 puffs a day at a moderately high nicotine dose (the equivalent of a heavy smoker trying to give up). The plan was to do this for a month.
Initially I did a lot of coughing and found the head rush unpleasant, but after a while I started to enjoy the experience. It was a bit like having a very strong cup of coffee, except the effects were almost instantaneous. Blowing smoke was also fun, in an adolescent sort of way, though my friends and family were not impressed.
What was vaping doing to my body, though? According to some scientists, quite a lot of damage. In a recent widely reported study ominously titled Electronic cigarettes induce DNA strand breaks and cell death, researchers found evidence that e-cigarettes are “as harmful as tobacco”.
Addictive or not, it seems nicotine by itself is not that bad for you They took human epithelial cells, the sort that line your mouth, trachea and lungs, and exposed them to vapour from e-cigarettes. Some of this vapour had nicotine in it, some didn’t. When they examined the cells afterwards they found DNA damage and cell death. Although there was more damage in the cells exposed to nicotine-laden vapour, it was still detectable in the nicotine-free vapour. This was the sort of damage that, according to the report, can “set the stage for cancer”. Scary stuff. The lead researcher was quoted as saying that e-cigarettes “are no better than smoking regular cigarettes”.
What the press release that promoted this study didn’t mention, and what most of the headlines missed, was that the researchers had also exposed some cells to tobacco smoke. The results of this were nothing short of cataclysmic. Most of the cells exposed to tobacco smoke died within 24 hours. By contrast, the cells exposed to e-cigarette vapour survived for up to eight weeks.
As a cancer charity researcher quickly tweeted, instead of the headline “Vaping no better than smoking regular cigarettes”, they could have said “Cells can survive for eight weeks in e-cig liquid but only 24 hours in cigarette extract”. Not, perhaps, quite as catchy.
To be honest, when I took up vaping I wasn’t that worried about the short-term health effects. There have been a number of major reports, such as the one from Public Health England, that state that e-cigarrettes are “around 95 per cent safer than tobacco”.
What I was far more concerned about was getting hooked on nicotine. Yet as the weeks went by and I puffed away, nothing happened. When I leapt out of bed I didn’t feel a longing to reach for my machine. If anything I struggled to keep up with my schedule. Once the novelty had worn off it became a bit of a chore.
Chatting to experts, I discovered to my considerable surprise that although cigarettes are highly addictive, nicotine alone may not be. Although no one knows for sure, research in animals suggests that nicotine is far more addictive when delivered in combination with the other chemicals found in regular cigarettes.
http://vapers.org.uk/smoke-and-mirrors-the-truth-about-vaping/
Horizon: E-Cigarettes: Miracle or Menace?
BBC Two – 9.30pm on Sunday 22nd May 2016
When the editor of the BBC science series Horizon asked me if I fancied making a programme about e-cigarettes that would involve “vaping” (inhaling nicotine-laden vapour) for a month my initial reaction was: “Hell, no.”
Then I thought about it a bit. I was worried that if I took it up I might get addicted (I’d never smoked), but I was also curious. What would it be like? What effect would it have on me? There has been a huge surge in the use of e-cigarettes over the past couple of years, yet very few studies on the effects of vaping on non-smokers. Time, I decided, to do one, with me as the subject.
I hate cigarettes, really hate them. I’ve never smoked, partly because when I was young I didn’t see the point, but mainly because when I was about 12 my dad offered me £100 if I didn’t smoke before the age of 18. I can’t remember if he ever paid me.
If I was even a little tempted to smoke, going to medical school put me off. One of the first patients I saw was Sarah, a 65-year-old woman who was dying of emphysema, a very common disease of the lungs caused by smoking. Even with an oxygen mask she struggled for breath. She’d been smoking 40 a day since she was 15 and she reckoned that she’d spent about £90,000 on cigarettes (at today’s prices it would be more like £290,000).
I also remember a young man called Alex with Buerger’s disease, a relatively rare condition where you get inflammation and clotting in your arteries and veins. Almost everyone who has Buerger’s smokes, and quitting smoking is the only way to stop it progressing. Despite knowing the risks Alex just couldn’t stop. He eventually developed gangrene and had to have a limb amputated.
Fans of e-cigarettes claim that vaping could help people like Alex and Sarah, either by making it easier for them to quit or by providing a safer way for them to get a nicotine hit. It is said that smokers smoke for the nicotine but die from the tar, so why not give them one and not the other?
Critics, however, say that we are gambling with a technology we don’t understand and that there is no convincing evidence that e-cigarettes help people to quit smoking. It may even encourage non-smokers to start.
There is a huge amount at stake. A billion people worldwide spend about £500 billion a year on cigarettes and about half will die of smoking-related diseases. In the UK alone smoking kills about 100,000 a year. If e-cigarettes take even a small fraction of the cigarette market, that is a lot of money and a lot of lives.
Some countries have warily embraced e-cigarettes, while others have effectively banned them. The UK has so far adopted a liberal approach, but in a few days’ time there will come into force European legislation that will limit the size of refills and the nicotine content of the fluids. Vaping will become more restricted.
So who’s right? Are e-cigarettes one of the greatest public health measures invented, with the potential to save millions of lives, or are they just another cunning way to keep us hooked on nicotine? I was keen to find out.
I started by having a range of physical and mental tests, including cognitive tests such as reaction times, then headed for my nearest e-cigarette shop. They come in lots of different shapes and sizes but all work on the same principle: there’s a battery that powers a heating element, a coil. There’s a chamber into which you pour your “e-liquid” which usually, but not always, contains nicotine. The heat from the coil turns the liquid into vapour, which you then inhale. There’s no burning and therefore fewer noxious chemicals involved. The e-liquids come in many flavours, from pina colada to menthol. I went for mint.
I bought a nice, geeky-looking device, with a big, shiny canister and lots of buttons. Then I went home to start vaping. I’d been given a schedule that began gently, then rapidly built to the point where I was taking about 120 puffs a day at a moderately high nicotine dose (the equivalent of a heavy smoker trying to give up). The plan was to do this for a month.
Initially I did a lot of coughing and found the head rush unpleasant, but after a while I started to enjoy the experience. It was a bit like having a very strong cup of coffee, except the effects were almost instantaneous. Blowing smoke was also fun, in an adolescent sort of way, though my friends and family were not impressed.
What was vaping doing to my body, though? According to some scientists, quite a lot of damage. In a recent widely reported study ominously titled Electronic cigarettes induce DNA strand breaks and cell death, researchers found evidence that e-cigarettes are “as harmful as tobacco”.
Addictive or not, it seems nicotine by itself is not that bad for you They took human epithelial cells, the sort that line your mouth, trachea and lungs, and exposed them to vapour from e-cigarettes. Some of this vapour had nicotine in it, some didn’t. When they examined the cells afterwards they found DNA damage and cell death. Although there was more damage in the cells exposed to nicotine-laden vapour, it was still detectable in the nicotine-free vapour. This was the sort of damage that, according to the report, can “set the stage for cancer”. Scary stuff. The lead researcher was quoted as saying that e-cigarettes “are no better than smoking regular cigarettes”.
What the press release that promoted this study didn’t mention, and what most of the headlines missed, was that the researchers had also exposed some cells to tobacco smoke. The results of this were nothing short of cataclysmic. Most of the cells exposed to tobacco smoke died within 24 hours. By contrast, the cells exposed to e-cigarette vapour survived for up to eight weeks.
As a cancer charity researcher quickly tweeted, instead of the headline “Vaping no better than smoking regular cigarettes”, they could have said “Cells can survive for eight weeks in e-cig liquid but only 24 hours in cigarette extract”. Not, perhaps, quite as catchy.
To be honest, when I took up vaping I wasn’t that worried about the short-term health effects. There have been a number of major reports, such as the one from Public Health England, that state that e-cigarrettes are “around 95 per cent safer than tobacco”.
What I was far more concerned about was getting hooked on nicotine. Yet as the weeks went by and I puffed away, nothing happened. When I leapt out of bed I didn’t feel a longing to reach for my machine. If anything I struggled to keep up with my schedule. Once the novelty had worn off it became a bit of a chore.
Chatting to experts, I discovered to my considerable surprise that although cigarettes are highly addictive, nicotine alone may not be. Although no one knows for sure, research in animals suggests that nicotine is far more addictive when delivered in combination with the other chemicals found in regular cigarettes.
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